Raynaud’s vasculitis

Image type:  Raynaud’s vasculitis Body site:  Hands and fingers Description:  Mixed connective-tissue disease (MCTD) is a disorder with features of systemic sclerosis (SSc), lupus erythematosus, and polymyositis. U1-ribonucleoprotein (RNP) antibodies are a specific marker of the disease. MCTD is considered a distinct syndrome and should not be confused with other connective-tissue disease overlap syndromes with … Read more

Remnant cholesterol can serve as a key predictor of rheumatoid arthritis

A recent study featured in Lipids in Health and Diseases has reported that elevated levels of remnant cholesterol (RC) are significantly associated with increased susceptibility to rheumatoid arthritis (RA). This groundbreaking finding underscores the potential of RC as a promising prognostic indicator for assessing the predisposition to RA.  The population-based study conducted by Dr. Yan … Read more

Baker’s cyst

Image type: Baker’s cyst Body Site: Knees Description: A Baker’s cyst is a fluid-filled cyst that causes a bulge and a feeling of tightness behind the knee. The pain can worsen when flexing or extending the knee or when active. A Baker’s cyst, also called a popliteal (pop-luh-TEE-ul) cyst, is usually the result of a … Read more

G protein-coupled receptor 30, a promising new target for treating osteoarthritis

A groundbreaking study published in the Journal of Orthopaedic Translation unveils the pivotal role of GPR30 activation in inhibiting ferroptosis within chondrocytes by suppressing Yes-associated protein 1 (YAP1) phosphorylation, thus modulating ferritin heavy chain 1 (FTH1) expression. These findings introduce a newer perspective on potential therapeutic interventions for osteoarthritis (OA), presenting G protein-coupled receptor 30 … Read more

Blood cadmium levels linked to higher mortality risk in rheumatoid arthritis patients

A new study, published in the Journal of Trace Elements in Medicine and Biology, reveals a concerning link between environmental cadmium exposure levels and  increased mortality risk among individuals with rheumatoid arthritis (RA). The findings underscore the potential impact of elevated blood cadmium levels on the health outcomes of RA patients, highlighting the effect of … Read more

Pregnancies in women with rheumatoid arthritis linked to Increased Adverse Outcomes

Women of childbearing age with rheumatoid arthritis (RA) have increased risks of adverse pregnancy outcomes, as indicated by findings from an 11-year nationwide study in France published in Rheumatic & Musculoskeletal Diseases Open.    The study, conducted by Pina and colleagues, utilized the French National Health Data System to analyze pregnancies concluded between 2010 and 2020, … Read more

Obesity management may positively impact patient outcomes in fibromyalgia

Fibromyalgia (FM) patients demonstrate an increased prevalence of comorbid conditions, particularly related to rheumatologic and psychiatric health, and the rates are much higher when compared to the general population. Recent research presented in Frontiers in Medicine, suggests that proactive intervention in addressing obesity may exert a profound influence on the overall outcomes for individuals grappling … Read more

Increased rheumatoid arthritis activity linked to diverse social and demographic factors

A recent study featured in BMC Rheumatology sheds light on the correlation between increased rheumatoid arthritis (RA) activity and a range of social  and demographic factors. These factors include age, income, gender, education, employment status, BMI, disease duration and retirement status.   Utilizing data from The University of Pittsburgh Rheumatoid Arthritis Comparative Effectiveness Research (RACER) registry, … Read more

Autoantibodies quiz: series 1

  [ays_quiz id=”57″] Welcome to the ‘Clinical Use of Autoantibodies in Rheumatology’ Quiz! Test your knowledge on the identification, significance, and clinical applications of autoantibodies in the context of rheumatological conditions.