Rheuma Tv

Serum metabolite signature panel may serve as a potential biomarker for the early clinical diagnosis of RA

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According to a study published in Frontiers in Immunology, a serum-based biomarker panel comprising glyceric acid, lactic acid, and 3-hydroxysovaleric acid has the potential to aid in the early diagnosis of rheumatoid arthritis (ERA).   The observational case-control study conducted by Dr. Rodríguez-Muguruza and colleagues performed untargeted metabolomic profiling of serum obtained from 32 patients with ERA and … Read more

The combination of tofacitinib and iguratimod may be effective in refractory RA and secondary OP

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According to a recent article published in the International Immunopharmacology, the combined application of tofacitinib and iguratimod may have a greater therapeutic effect on refractory rheumatoid arthritis (RRA) and its associated osteoporotic bone remodeling. In the rat model of collagen-induced arthritis (CIA) + tumor necrosis factor (TNF), the use of tofacitinib and iguratimod showed significant … Read more

Practice of yoga can boost immune regulation and decrease the severity in RA

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Rheumatoid Arthritis (RA) is caused by an imbalance of Th17/Treg cells due to a pro-inflammatory environment. T cells in RA show signs of aging and DNA damage, increasing the risk of mutations. According to a recent study published in Scientific Reports, yoga can reduce disease activity, balance Th17/Treg cells, and optimize cytokine levels while altering … Read more

Oral Hydroxychloroquine is safe and effective in treating primary Sjögren’s syndrome-related dry eye disease

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Patients with primary Sjögren’s syndrome (pSS) often experience dry eye disease. Hydroxychloroquine (HCQ) has become a significant treatment option for pSS due to its immunomodulatory effects and minimal adverse effects. A recent study published in Alternative Therapies in Health and Medicine demonstrated the effectiveness and safety of HCQ in pSS patients with moderate to severe … Read more

Neutrophil cytosolic factor 4 may serve as a potential biomarker for ankylosing spondylitis

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In recent years, biomarkers have gained prominence in the pursuit of early diagnosis for ankylosing spondylitis (AS) and in the selection of appropriate treatment for patients. A recent article published in the Journal of Musculoskeletal and Neuronal Interactions suggests that Neutrophil Cytosolic Factor 4 (NCF4) could serve as a diagnostic and prognostic biomarker for AS.  … Read more

Chitinase-3 like-protein-1 may serve as a potential biomarker in RA patients with interstitial lung disease

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Interstitial lung disease (ILD) is a common complication of rheumatoid arthritis (RA), which can lead to serious health problems and even death. A recent article published in Frontiers in Immunology reported increased levels of chitinase-3 like-protein-1 (CHI3L1) in patients with RA-ILD and suggested its promising role as a biomarker.  The study conducted at the Department … Read more