Rheuma Tv

Neuropathic pain (NP), is a disruptive symptom associated with many diseases, which results in restricted physical function, anxiety, and depression. A recent systematic review and expert consensus published in Frontiers of Medicine has reported that exercise is very helpful in alleviating the intensity of neuropathic pain. The newer expert recommendation highlights the need to consider … Read more

Glucocorticoids serve as the mainstay of treatment for managing polymyalgia rheumatic treatment. However, longer treatment duration and steroid-related adverse events are the major challenges in using them in routine practice. Moreover, there are no glucocorticoid-sparing agents with proven therapeutic potential for managing polymyalgia. A recent study published in the Lancet Rheumatology has concluded on the … Read more

Abnormal cytokine tumor necrosis factor (TNF) production has been identified as the key pathogenic event responsible for autoimmune tissue inflammation. A recent study published in Nature Immunology has demonstrated that mitochondrial aspartate is a key regulator of TNF biogenesis and its defective production, in turn, causes enhanced TNF biogenesis, resulting in rheumatoid tissue inflammation. Wu … Read more

There are no preventive measures for rheumatoid arthritis (RA) and for the past few decades, researchers have been exploring the possibility of having a vaccine. CEL-SCI Corporation, a biotechnology company, in collaboration with scientists at Rush university medical centre, USA, has developed a T cell-targeting vaccine called CEL-4000. In animal models, it was able to … Read more

The 2021 guidelines published by the American College of Rheumatology (ACR) provide recommendations for deciding on the treatment interventions based on the routine clinical challenges. This update focuses on the onset and adjustment of DMARD therapy and the significance of reducing glucocorticoid use. The periodic revisions of the ACR guidelines assist in achieving the desired … Read more

The findings of a double-blind, withdrawal phase III study, published in Lancet, have reported the safety and efficacy of tofacitinib in managing patients with polyarticular course juvenile idiopathic arthritis (JIA). The study was carried out at 64 centers of the Paediatric Rheumatology International Trials Organisation and Pediatric Rheumatology Collaborative Study Group networks across 14 countries … Read more

The introduction of COVID-19 vaccines is a sign of relief amidst of coronavirus pandemic around the world. However, a hesitancy for vaccination has been developed among rheumatoid arthritis (RA) patients owing to the suspicion of arthritis flare after vaccination. Recent research shows that there is no link between COVID-19 vaccines full doses and arthritis flare … Read more