What are the typical joint paterns and extra-articular features of IBD-associated arthritis compared to axSpA?

IBD-associated arthritis presents with distinct patterns that differ from typical axSpA, as listed in table 1.

Table 1: Comparison of joint paterns and extra-articular features in IBD-associated arthritis vs. axSpA

 

Feature

IBD-associated arthritis

axSpA

Main joint pattern

Peripheral, asymmetric oligoarthritis

Axial (SI joints, spine), symmetric

Joint distribution

Lower limbs (knees, ankles); sometimes upper limbs

Spine and SI joints; less often peripheral joints

Erosiveness

Typically non-erosive

Can progress to new bone formation (ankylosis)

Course with disease

Flares with bowel activity (peripheral); axial may not

Often independent of gut flares

Enthesitis, dactylitis

Possible, less prominent

Enthesitis central; dactylitis less common

Eye involvement

Uveitis

Uveitis

REFERENCE

  1. Orchard Management of arthritis in patients with inflammatory bowel disease. Gastroenterol Hepatol (N Y). 2012 May;8(5):327-9. PMID: 22933865; PMCID: PMC3424429.
  2. Amiri AH, Hosseini V, Roodposhti FN. Pattern of peripheral arthritis in fifteen patients with ulcerative Journal of Medical Society. 2015 Dec;29(3):135.