[Day-1] Lecture Series 4 (Autoimmunity and Inflammation)

Dr. Sudheeran discussed the clinical perspective of neuroinflammatory diseases. Co-existence of other autoimmune diseases like vitiligo, signs of thyrotoxicosis/hypothyroidism, evidence of polyarthritis, rashes, orogenital ulcers, cachexia, and hyperpigmentation helps to identify autoimmune neurological diseases. In 60-70% of paraneoplastic encephalitis cases, paraneoplastic antibodies are the neuroimmunological markers. The immunopathological mechanism of Neuroinflammatory Diseases was discussed by … Read more

Investigations in Rheumatology Series-3

[presto_player id=1579] Discussion on technique, methods, and characteristic features of CRP ESR, NLR by Dr. Renuka. ESR is a prognostic test useful in monitoring inflammatory disease and response to therapy. CRP is a predictive marker in atherosclerosis, CHF, Atrial fibrillation, myocarditis, aortic valve disease, and heart transplantation as it is a clinical measure of inflammation … Read more

Is dengue virus another viral trigger for SARDS?

Systemic inflammatory rheumatic diseases (SARDS) are often linked to a trigger by a viral infection such as Epstein-Bar Virus and cytomegalovirus. According to a new study, dengue has been attributed to be a trigger or associated with SARDS. An interest nationwide, population-based case-control study conducted among 17,126 subjects found that a history of dengue fever … Read more

Cardiovascular and malignancy risk with janus kinase inhibitor is it dose dependent

Janus kinase (JAK) inhibitors, a new class of targeted synthetic disease-modifying antirheumatic medicines (DMARDs), have been demonstrated to be safe and effective in rheumatoid arthritis (RA) and are currently being explored extensively in autoimmune and inflammatory illnesses. The Food and Drug Administration (FDA) has issued new cautions for several (JAK) inhibitors. The FDA has noted … Read more

Finally! a definition for difficult-to-treat rheumatoid arthritis

A recent study published in the Annals of Rheumatic Diseases has proposed European League Against Rheumatism (EULAR) definition for difficult-to-treat RA, which could be beneficial in clinical practice, clinical trials, and future research. The 3 criteria proposed by the EULAR task force members for defining difficult-to-treat RA are as follows: (1) Treatment according to the … Read more

Approach To Diagnosis And Treatment Of Rheumatoid Arthritis

Do you have an update on approaches to the diagnosis and treatment of rheumatoid arthritis?

It is necessary to perform a joint examination for tenderness, range of movement, deformities, and other abnormalities in the diagnosis of Rheumatoid arthritis. High titers of rheumatoid factor indicate aggressive, destructive joint disease and extra-articular complications. It is important to exclude the monoarthritis conditions before diagnosing Rheumatoid arthritis. To learn more, watch the lecture on the approach to diagnosis and treatment of rheumatoid arthritis given by Dr. Ashwini Kamath.

History taking and Interpretation in Back Pain

Dr. Shruthi Desai discussed the history taking and interpretation of symptoms concerning back pain. History taking is important in back pain as the causes of it can be multifactorial i.e., simple muscular strain to life-threatening issues. 80-90% of the causes of back pain are mechanical. The causes of back pain are classified into primary back … Read more

Investigation in Rheumatology, Session – 2

[presto_player id=1332] Dr. Renuka discussed investigative methods and applications of Rheumatoid factor (RF), Anti-CCP & new autoantibodies in Rheumatology. RF and Anti-CCP are remarkable antibodies currently used in the diagnosis and provide different clinical and pathophysiological information. Anti-CCP is more specific and has a high predictive value for RA development compared to RF. Dr. Chandrashekara. … Read more

Risk of COVID-19 infection with Interstitial Lung Disease

Interstitial lung disease ILD is a wide range of conditions, and the majority of them result in progressive scarring of lung tissue. This in turn limits the breathing capacity and the amount of oxygen in the bloodstream. Long-term exposure to hazardous materials, such as asbestos, can induce ILD. It can also be caused by autoimmune … Read more