Family history of autoimmune diseases increases the risk for juvenile idiopathic arthritis

Results from the international Pharmachild registry have proven a family history of autoimmune disease as a significant risk factor for juvenile idiopathic arthritis (JIA), however, it does not have an effect on disease severity. The study findings are published in the recent issue of Pediatric Rheumatology. Joeri W. van Straalen and co-researchers analyzed the data … Read more

Study shows association between autoimmune disorders and new-onset atrial fibrillation

There is substantial literature to validate the role of inflammation and the innate immune system in developing myocardial infarction, cerebrovascular events, and heart failure. Now a recent study published by a group of researchers from the University Medical Center Rotterdam, Netherlands, has reported that various autoimmune diseases are linked to new-onset atrial fibrillation, especially in … Read more

Study links physical inactivity levels with higher pain scores, depression rates in RA patients

Over the past few decades, regular physical exercise has been recognized as an important component of RA management, and the benefits include reduced inflammation and pain, and improved muscle force, aerobic capacity, and quality of life. “However, the proportion of elderly adhering to the proposed physical activity guidelines is only 27% to 44%. According to … Read more

Neural stem cell transplantation shows promise in preventing progressive multiple sclerosis

Multiple sclerosis (MS), a chronic neuroinflammatory and neurodegenerative disease, is often disabling and poses substantial physical, psychological, and social burden on society and patients. The disease affects nearly 2.8 million subjects worldwide with an average lifespan ranging from 25 to 35 years following diagnosis. Although, several treatments are available to reduce the symptoms, there is … Read more

First-ever ACR guidelines recommending integrative approach for the management of rheumatoid arthritis released

The American College of Rheumatology (ACR) has released its first-ever integrative approach for the management of rheumatoid arthritis (RA) and the new guidelines include recommendations for exercise, rehabilitation, diet, and additional integrative interventions. The details of the new guidelines, which will complement the ACR’s 2021 guideline for the treatment of RA, are expected to be … Read more

Studies recommend continuation of low-dose steroid reduces the risk of flare in rheumatoid arthritis patients on bDMARDs

Despite several studies reporting the severe adverse events associated with chronic glucocorticoid use, they are still prescribed as the mainstay of treatment in routine practice to reduce inflammation and disease activity. The 2019 European League Against Rheumatism (EULAR) recommendations have also strongly advocated tapering glucocorticoids to the lowest possible dose for the effective management of … Read more

Systematic review on the association between concomitant rheumatoid arthritis and peripheral arterial disease

Rheumatoid arthritis (RA) has been recognized as an independent risk factor for cardiovascular diseases. The risk is accentuated by the use of steroids for the management of associated flares, atherosclerotic changes contributed by disease inflammation, and associated vascular morbidities such as peripheral arterial disease (PAD). Now, the findings of a systematic review published in Rheumatology … Read more