Autoantibodies quiz: series 1

 

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Autoantibodies quiz: series 1

Welcome to the ‘Clinical Use of Autoantibodies in Rheumatology’ Quiz! Test your knowledge on the identification, significance, and clinical applications of autoantibodies in the context of rheumatological conditions.

1 / 8

Which is the primary immunoglobulin class most commonly associated with rheumatoid factor (RF), and what part of the immunoglobulin does RF typically bind?

2 / 8

Citrullination leads to the post-translational modification of which amino acids?

3 / 8

Apart from anti-citrullinated peptide antibodies (ACPAs), what other autoantibodies, associated with rheumatoid arthritis, are mentioned as unlikely to add diagnostic value and are not routinely tested for?

4 / 8

Which was the first citrullinated autoantigen used in RA studies, and how was it modified for diagnostic assays?

5 / 8

Which anti-modified peptide antibody (AMPA) is associated with antibodies against carbamylated or homocitrulline-containing proteins?

6 / 8

Which enzyme is responsible for citrullination in the generation of citrullinated peptides?

7 / 8

Which autoantibody has been described as a marker for an acute onset RA subgroup with a good prognosis?

8 / 8

Which human leukocyte antigen (HLA) alleles are associated with an increased risk of having ACPA-positive rheumatoid arthritis (RA) and are linked to both the development of RA and ACPA-positive RA?

Welcome to the ‘Clinical Use of Autoantibodies in Rheumatology’ Quiz! Test your knowledge on the identification, significance, and clinical applications of autoantibodies in the context of rheumatological conditions.

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